Kurkuma 95% ekstrakt & BioPerine®

Standardized and highly purified turmeric root extract

Kurkuma 95% ekstrakt & BioPerine

Turmeric – queen of health from India

Dry turmeric root extract (Curcuma longa) standardized on 95% curcuminoydes and dry extract of Black Pepper (Piper nigrum) BioPerine® standardized on 95% piperine

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22,99 € (173,22 kn)

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Turmeric (lat. Curcuma longa) is a spice obtained from an underground tree (rhizome) of the eponymous plant characteristic of India and Southeast Asia. Turmeric has a rich history in India as a spice, preservative and colorant, and has been used for centuries in Ayurvedic medicine where it is well documented as a natural remedy.

The characteristic yellow color of turmeric is due to the polyphenol curcumin, an active ingredient from the group of curcuminoids.

Native curcumin is excreted from the body unused very quickly, ie it has extremely low bioavailability.

What is bioavailability?
Bioavailability is the ratio of the amount of nutrients in the body to the part of the nutrients that is actually digested, absorbed and metabolized by conventional biochemical processes. It is that part of the dose of a drug or dietary supplement that is truly available to act on the target site.

Bioavailability is an important factor in the performance of a product, but not the only one on the basis of which the product is compared and on the basis of which its effectiveness is assessed.

To the product Turmeric 95% extract & Bioperine® was added the ingredient piperine or its patented and protected form Bioperine® – black pepper extract that enhances the action and absorption of curcumin in body cells up to 20 times.

You can find out more about the bioavailability of curcumin at: https://hugyourlife.eu/bioraspolozivost-kurkumina/

A clinical study from St. John Medical College and published in Planta Medica provided clinical evidence of the role of piperine in increasing the bioavailability of curcumin (Majeed M. et al. (1998). Planta Med.; 64 (4): 353-356).

The action of curcumin is incomparably stronger than the action of turmeric spice due to the fact that turmeric spice contains a maximum of 3-5% curcuminoids while the extract contains 95% curcuminoids.

Ingredients:
Dry extract of turmeric rhizome (Curcuma longa) containing at least 95% curcuminoids, thickener: hydroxypropyl methyl cellulose (capsules), anti-caking agent: microcrystalline cellulose, dry extract of black pepper (Piper nigrum), anti-caking agent: cellulose powder (ARBOCEL® A300).

Ingredients:	In 2 capsules (daily dose)
Dry extract of Turmeric root (Curcuma longa) standardized to at least 95% curcuminoids	700 mg
Dry extract of Black Pepper fruit (Piper nigrum) BioPerine®: standardized to at least 95% piperine	10 mg

BioPerine® is a 95% extract obtained from black pepper that is grown in moist and nutritious soil in the regions of South India. Piperine extract, called BioPerine® in patented form, is the only black pepper extract to have proven its safety and efficacy in food use (GRAS status) through clinical studies in the United States.

More about the standardized and patented BioPerine® black pepper extract can be found here: http://www.bioperine.com/

Turmeric and its active component, curcumin, are record holders in that more than 11,000 biomedical studies published on PubMed are associated with their study (Alzheimer’s, Arthritis, Chron, Epstein Barr, Ulcerative Colitis, Cancer, Cholesterol, Diabetes ().

Instructions for use:
It is recommended to take 1-2 capsules a day best during meals.

Notes:
The recommended daily doses should not be exceeded. A dietary supplement is not a substitute or replacement for a balanced diet. Keep out of reach of small children. It is important to adhere to a balanced and varied diet and a healthy lifestyle. The capsules have a neutral taste and smell, 100% from a plant source, and are also suitable for vegetarians.

Warnings:
People taking medication should consult a doctor before taking it. Not recommended for digestive disorders, thyroid disease, pregnant and lactating women.

Storage conditions:
In a dry and dark place at a temperature up to 25 ° C.

Turmeric 95% Extract & BioPerine® is a product based on dry extract of Turmeric root (Curcuma longa) standardized to at least 95% curcuminoids and dry extract of Black Pepper fruit (Piper nigrum) BioPerine® standardized to at least 95% piperine.

Literature:

Planta Med. 1998; 64(4): 353-6
Srinivasan K. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Crit Rev Food Sci Nutr. 2007;47(8):735-748.
Hiwale AR, Dhuley JN, Naik SR. Effect of co-administration of piperine on pharmacokinetics of beta-lactam antibiotics in rats. Indian J Exp Biol. Mar 2002;40(3):277-281.
Lambert JD, Hong J, Kim DH, Mishin VM, Yang CS. Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice. J Nutr. Aug 2004;134(8):1948-1952.
Atal CK, Dubey RK, Singh J. Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism. J Pharmacol Exp Ther. Jan 1985;232(1):258-262.
Khajuria A, Zutshi U, Bedi KL. Permeability characteristics of piperine on oral absorption–an active alkaloid from peppers and a bioavailability enhancer. Indian J Exp Biol. Jan 1998;36(1):46-50.
Zeng, Y., Qiu, F., Takahashi, K., Liang, J., Qu, G., and Yao, X. New sesquiterpenes and calebin derivatives from Curcuma longa. Chem.Pharm Bull.(Tokyo) 2007;55(6):940-943
Zhang, L., Fiala, M., Cashman, J., Sayre, J., Espinosa, A., Mahanian, M., Zaghi, J., Badmaev, V., Graves, M. C., Bernard, G., and Rosenthal, M. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer’s disease patients. J Alzheimers.Dis. 2006;10(1):1-7.
Zhou, G., Wang, J. F., Niu, J. Z., Lu, Y. S., Chen, W. T., Li, Z. H., and Lin, T. X. [Experimental study on protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats]. Zhongguo Zhong.Yao Za Zhi. 2006;31(7):570-573.
Allen, S. W., Mueller, L., Williams, S. N., Quattrochi, L. C., and Raucy, J. The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression. Drug Metab Dispos. 2001;29(8):1074-1079.
Antony B, Kizhakedath R Benny M Kuruvilla BT. Clinical Evaluation of a herbal product (Rhulief™) in the management of knee osteoarthritis. Abstract 316. Osteoarthritis Cartilage 2011;19(S1):S145-S146.
Antony S, Kuttan R, Kuttan G. Immunomodulatory activity of curcumin. Immunol Invest 1999;28:291-303..
Appiah-Opong, R., Commandeur, J. N., Vugt-Lussenburg, B., and Vermeulen, N. P. Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products. Toxicology 6-3-2007;235(1-2):83-91.
Araujo CC, Leon LL. Biological activities of Curcuma longa L. Mem Inst Oswaldo Cruz 2001;96:723-8.
Baum L, Lam CW, Cheung SK, et al. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease (letter). J Clin Psychopharmacol 2008;28:110-3.
Belcaro G, Cesarone MR, Dugall M, et al. Efficacy and safety of Meriva, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Alt Med Rev 2010:15:337-4.
Calaf GM, Echiburú-Chau C, Wen G, Balajee AS, Roy D. Effect of curcumin on irradiated and estrogen-transformed human breast cell lines. Int J Oncol. 2012;40(2):436-42
Carroll RE, Benya RV, Turgeon DK, et al. Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia. Cancer Prev Res (Phila) 2011;4:354-64.
Choi, B. H., Kim, C. G., Lim, Y., Shin, S. Y., and Lee, Y. H. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. Cancer Lett. 1-18-2008;259(1):111-118
Deeb D, Xu YX, Jiang H, et al. Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. Mol Cancer Ther 2003;2:95-103.

Curcumin is an active ingredient from the group of curcuminoids to which we attribute a therapeutic effect, and is obtained by extraction from turmeric root. Curcumin in Turmeric 95% Extract & Bioperine® is patented and standardized.

In addition to turmeric and its active component, curcumin has been linked to more than 11,000 biomedical studies published on PubMed (Alzheimer’s, Arthritis, Chron, Epstein Barr, Ulcerative Colitis, Cancer, Cholesterol, Diabetes ()

This means that Turmeric 95% & BioPerine® contains a continuous composition in each batch for turmeric extract as well as for black pepper extract, BioPerine®. High purity of the extract is important for the bioavailability of the active substance because the higher the purity, the better the bioavailability of curcumin.

This means that Curcumin C3Complex® contains a continuous composition in the same proportions in each batch for all 3 curcuminoids as for the black pepper extract, BioPerine®.

It is recommended to take 1-2 capsules daily, preferably during meals. Since Turmeric is 95% & BioPerine® herbal extract, more than the recommended daily dose can be taken. Clinical studies have shown that the human body can tolerate 12 grams of curcuminoids per day without side effects.

People taking medication should consult a doctor before taking it. Not recommended for digestive disorders, thyroid disease, pregnant and lactating women. Restrictions apply only to BioPerine® black pepper extract.

Bioavailability is the ratio of the amount of nutrients in the body to the part of the nutrients that is actually digested, absorbed and metabolized by conventional biochemical processes. Simply put, it is that part of the dose of a drug or dietary supplement that is truly available to act on the target site
BioPerine® was added to the product to increase the bioavailability of curcumin and thus make it more usable in our body up to 20 times.
BioPerine® significantly increases the bioavailability of various nutrients through increased absorption.

You can find out more about the bioavailability of curcumin at: https://hugyourlife.eu/bioraspolozivost-kurkumina/
You can find out more about BioPerine® bioavailability at: http://www.bioperine.com/

Rated 5 out of 5
Anoniman
Odličan proizvod, za preporuku!!
Rated 5 out of 5
Ana Milanović
Super! Zato stalno i naručujem novi 😊
Rated 5 out of 5
Mladen Belobaba
Odlican proizvod, sve preporuke..
Rated 5 out of 5
Anoniman
Kurkumu uzimam redovno kao pomoć kod bolova u mišićima i zglobovima.
Rated 5 out of 5
Danko B.
Uzimamo je svi u obitelji, preporučam svima.
Rated 5 out of 5
Božica Balaš
Super
Rated 5 out of 5
Anoniman
Dijelomicno pomogle nakon mjesec dana koristenja.
Rated 4 out of 5
Anonymous
Još nisam popila sve kapsule, tako da očekujem da se još bolje osjećam.
Rated 5 out of 5
Jelena R.
Iznimno sam zadovoljna proizvodom. Inače uzimam kurkumu u prahu, ali korištenjem ekstrakta kurkume puno brže se vide rezultati.

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Kurkuma 95% ekstrakt & BioPerine®

Standardized and highly purified turmeric root extract